Lung cancer, the growth of malignant cells in the lungs, and is the leading cause of death from cancer in the United States for both men and women. The types of primary lung cancer (cancer that originates in the lungs) may be grouped into two categories: small-cell carcinoma and non-small-cell carcinoma. Non-small-cell carcinoma comprises several types of lung cancers and is responsible for up to 80 percent of cases. The outlook is poor for all types of lung cancer unless the cancer is detected very early and can be surgically removed. Small-cell carcinoma is the most difficult to treat as it is often diagnosed after it has spread to many organs. Despite being very responsive to chemotherapy and radiotherapy, individuals with small cell carcinoma commonly relapse within a year.
Primary lung cancer can spread to essentially any organ. Where it may produce more disabling symptoms. Most cases occur between ages 45 and 75, after years of exposure to cigarette smoke or other pollutants. In many instances, the disease is preventable: over 90 percent of cases are caused by smoking. Nonsmokers have only a small risk, and those who quit smoking even after smoking for years greatly reduce their risk. The lungs are also a frequent site of secondary cancer, which has spread from elsewhere in the body. Such tumors are almost always incurable.
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